Atorvastatin Calcium (Lipitor)

Photograph of Atorvastatin Calcium (Lipitor) under the microscope.

Lipitor is classified as a synthetic antihyperlipidemic that acts to lower lipid levels in the body by blocking its ability to synthesize cholesterol. The pharmaceutical agent works by specific inhibition of HMG-CoA reductase, an enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) to mevalonate, an early step in cholesterol biosynthesis. By blocking cholesterol synthesis, lipitor reduces the risk of heart disease and/or stroke. When response to diet and other non-drug measures alone are inadequate to reduce cholesterol levels, lipitor is indicated to lower total and LDH cholesterol levels in primary hypercholesterolemia (types IIa and IIb). Side effects include diarrhea, gas, headache, joint pain, nausea, vomiting, and stomach pain.

© 1995-2013 by Michael W. Davidson and The Florida State University. All Rights Reserved. No images, graphics, software, scripts, or applets may be reproduced or used in any manner without permission from the copyright holders. Use of this website means you agree to all of the Legal Terms and Conditions set forth by the owners.
This website is maintained by our
Graphics & Web Programming Team
in collaboration with Optical Microscopy at the
National High Magnetic Field Laboratory.
Last modification: Monday, Sep 20, 2004 at 10:39 AM
Access Count Since March 2, 2000: 65001