Chlorothiazide (Diuril)

Photograph of Chlorothiazide under the microscope.

Chlorothiazide is a thiazide diuretic that is used to reduce high blood pressure in both adults and children. The specific mechanism of action of the thiazide diuretics is unknown, but they seem to affect the distal renal tubular mechanism of electrolyte reabsorption. Side effects include the loss of too much potassium and/or sodium in the urine and less commonly, diarrhea, dizziness, and increased sensitivity to sunlight.

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