Isotretinoin (Accutane)

Photograph of Isotretinoin (Accutane) under the microscope.

Isotretinoin is a retinoid that is widely used in the treatment of severe (often disfiguring) nodular acne, primarily in adolescents. Although the exact mechanism of action is unknown, isotretinoin acts by inhibition of sebaceous gland function and keratinization. This retinoic acid derivative is also used to treat other skin diseases, although it is known to cause birth defects in humans and should be used with extreme caution (preferably not at all) during pregnancy. Side effects are not common, but include chest pain, dizziness, fast heartbeat (more common for injection), and skin rash.

© 1995-2013 by Michael W. Davidson and The Florida State University. All Rights Reserved. No images, graphics, software, scripts, or applets may be reproduced or used in any manner without permission from the copyright holders. Use of this website means you agree to all of the Legal Terms and Conditions set forth by the owners.
This website is maintained by our
Graphics & Web Programming Team
in collaboration with Optical Microscopy at the
National High Magnetic Field Laboratory.
Last modification: Wednesday, Mar 03, 2004 at 04:33 PM
Access Count Since May 15, 1999: 41429